SYRE Spyre Therapeutics, Inc.
$90.60▲ +2.13%
Healthcare
Other
After hours
$90.60▲ +0.00%
Sep 11, 7:30 PM ET
Volume 886.1K
Avg Volume (10D) 1.22M
Key Metrics & Fundamentals
Market Cap
$7.99B
P/E Ratio
–
Div Yield
–%
52W Range
14.51 - 110.18
% vs 50 MA
-7.65%
% vs 200 MA
43.15%
RSI-14
42.8
MACD Histogram
-0.8500
Beta (1Y vs SPY)
1.87
Free Cash Flow
-$69.88M
Gross Rev
$0
Gross Profit
$0
EBITDA
-$121.64M
COGS
–
Operating Exp
$81.64M
Operating Income
-$81.64M
EBIT
-$81.64M
Pretax Income
-$36.20M
Net Income
-$36.20M
EPS (Diluted)
-0.43
Price & Volume History
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Recent News

Spyre Therapeutics (SYRE) Reports SPY003 Endoscopic Improvement. Can Randomized Testing Confirm It?
Insider Monkey · Sep 10, 2026 11:59 PM

Spyre's Anti-IL-23 Antibody Meets Goal in Ulcerative Colitis Study
Zacks · Sep 9, 2026 1:56 PM
Spyre Therapeutics' SPY003 Meets Phase 2 Primary Endpoint in Ulcerative Colitis
MT Newswires · Sep 8, 2026 1:35 PM

Spyre Announces Potential Best-in-Class SPY003 (anti-IL-23) Part A Induction Results from SKYLINE Trial, Completing Proof-of-Concept for All Three Components of its IBD Combinations
GlobeNewswire · Sep 8, 2026 12:00 PM

Spyre Therapeutics Announces Grants of Inducement Awards
GlobeNewswire · Sep 4, 2026 8:01 PM
Spyre Therapeutics Insider Sold Shares Worth $2,480,529, According to a Recent SEC Filing
MT Newswires · Sep 4, 2026 7:41 AM
Spyre Therapeutics Insider Sold Shares Worth $2,283,821, According to a Recent SEC Filing
MT Newswires · Sep 4, 2026 7:30 AM
Spyre Therapeutics Insider Sold Shares Worth $1,309,410, According to a Recent SEC Filing
MT Newswires · Sep 4, 2026 7:30 AM

Spyre Therapeutics to Participate in Upcoming September Investor Conferences
GlobeNewswire · Sep 3, 2026 8:05 PM

Spyre Therapeutics (SYRE) Down 16.6% Since Last Earnings Report: Can It Rebound?
Zacks · Sep 3, 2026 3:30 PM
Financial Overview - Income Statement
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