IONS Ionis Pharmaceuticals, Inc.

$73.32▼ -1.69% Unknown Other Last sync: just now Syncing
Key Metrics & Fundamentals
Market Cap
$12.12B
P/E Ratio
Div Yield
–%
52W Range
34.78 - 86.74
% vs 50 MA
-0.55%
% vs 200 MA
0.81%
RSI-14
48.5
MACD Histogram
-0.1700
Beta (1Y vs SPY)
0.40
Free Cash Flow
-$816.07M
Gross Rev
$246.09M
Gross Profit
$243.09M
EBITDA
-$112.59M
COGS
$3.00M
Operating Exp
$360.57M
Operating Income
-$117.48M
EBIT
-$117.48M
Pretax Income
-$92.31M
Net Income
-$92.53M
EPS (Diluted)
-0.56
Price & Volume History
Volume (M)
Financial Overview - Income Statement Quarterly
AI Analysis
Generated May 28, 2:47 AM
Company Overview

Ionis Pharmaceuticals, Inc. is a leading biotechnology company specializing in the discovery and development of RNA-targeted therapeutics. Leveraging its proprietary antisense technology platform, Ionis aims to address a wide range of diseases with high unmet medical needs. The company maintains a competitive position through its extensive pipeline and strategic partnerships with major pharmaceutical companies.

Bull Case
  • Ionis possesses a robust pipeline of RNA-targeted therapies, with several drugs in advanced clinical stages and a proven proprietary antisense technology platform, providing multiple shots on goal.
  • Strategic collaborations with large pharmaceutical companies provide significant non-dilutive funding, shared development costs, and broader market access, de-risking its drug development efforts.
  • The company has multiple approved products on the market, generating recurring revenue and validating the efficacy and safety of its core technology.
  • Technical indicators are positive, with the stock trading above both its 50-day and 200-day moving averages, suggesting a healthy upward trend and strong underlying momentum.
Bear Case
  • The absence of a P/E ratio (N/A) indicates the company is not currently profitable, which is common for biotech but signals reliance on future drug approvals and sales for sustained financial performance.
  • As a biotechnology company, Ionis faces inherent risks associated with clinical trials, where drug candidates can fail at any stage, leading to significant R&D write-offs and stock volatility.
  • The pharmaceutical industry is highly competitive, with potential for new entrants, competing therapies, or patent expirations to erode market share and profitability of Ionis's products.
  • Drug development is subject to stringent and unpredictable regulatory approval processes, which can cause delays, increase costs, or result in outright rejection, impacting the commercialization timeline and success.
Recent Performance

Ionis Pharmaceuticals is currently trading at $76.49, showing a daily gain of +0.6%. While it is 11.8% below its 52-week high, the stock has demonstrated strong upward momentum, trading +2.3% above its 50-day moving average and +5.1% above its 200-day moving average. The RSI-14 at 53.9 indicates neutral momentum, suggesting the stock is neither overbought nor oversold and has room for potential further movement within its established trend.

AI-generated analysis is for informational purposes only and does not constitute financial advice.

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